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2-11-09: Gene expression study of cancer
Prof. Chris T. Man - CTMAN@txccc.org
Biomarker discovery from gene expression and serum MALDI-TOF data. Discovery of prognostic and predictive biomarkers from gene expression and mass spectrometry data using feature selection and unsupervised learning.
Focus paper (see also Comp Lab exercise for this week):
Expression profiles of osteosarcoma that can predict response to chemotherapy. Cancer Res. 2005 Sep 15;65(18):8142-50. PMID: 16166288 [PubMed - indexed for MEDLINE]
Other relevant papers:
Classification of sarcomas using bioinformatics and molecular profiling. Curr Pharm Biotechnol. 2007 Apr;8(2):83-91. Review. PMID: 17430156 [PubMed - indexed for MEDLINE]
Identification of a plasma proteomic signature to distinguish pediatric osteosarcoma from benign osteochondroma. Proteomics. 2006 Jun;6(11):3426-35. PMID: 16673437 [PubMed - indexed for MEDLINE]
Focus paper (see also Comp Lab exercise for this week):
Expression profiles of osteosarcoma that can predict response to chemotherapy. Cancer Res. 2005 Sep 15;65(18):8142-50. PMID: 16166288 [PubMed - indexed for MEDLINE]
Other relevant papers:
Classification of sarcomas using bioinformatics and molecular profiling. Curr Pharm Biotechnol. 2007 Apr;8(2):83-91. Review. PMID: 17430156 [PubMed - indexed for MEDLINE]
Identification of a plasma proteomic signature to distinguish pediatric osteosarcoma from benign osteochondroma. Proteomics. 2006 Jun;6(11):3426-35. PMID: 16673437 [PubMed - indexed for MEDLINE]
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